Serum inhibin concentrations, determimed by radioimmunoassay, were measured in women undergoing pituitary suppression with Decapeptyl and subsequently ovarian stimulation with Highly Purified-Metrodin (HP-FSH) to appraise follicular development.
Early
follicular basal serum inhibin level correlated with the number of oocytes retrieved (r=0.89, n=8, p<0.05). The number of oocytes retrieved showed a significant correlation with serum inhibin level on the day of hCG administration (r=0.73, n=8,
p<0.05).
The number of mature oocytes showed a significant correlation with serum inhibin level on the day of hCG administration (r=0.73, n=8, p<0.05). These data suggest that: (1) In the early follicular phase, basal serum inhibin may be a valid index to
predict ensuing follicular growth: (2) In the preovulatory phase, maximum serum inhibin may be one of the applicable indexes of follicular development during hyperstimulation cycles.
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